Treatment with RYBREVANT® (amivantamab-vmjw) + Chemo Resulted in Statistically Significant and Clinically Meaningful Improvement in PFS in Patients with Newly Diagnosed EGFR Exon 20 Insertion Mutation-Positive NSCLC

“The results from the PAPILLON study support the efficacy of RYBREVANT plus chemotherapy in the treatment of patients with non-small cell lung cancer with exon 20 insertion mutations,” said Peter Lebowitz, M.D., Ph.D., Global Therapeutic Area Head, Oncology, Janssen Research & Development, LLC. “RYBREVANT was the first therapy approved in the relapsed/refractory setting for patients with EGFR exon 20 insertion mutations, a population that continues to experience persistent unmet medical needs. This Phase 3 study is the first of several ongoing pivotal programs to read out evaluating RYBREVANT-based regimens in patients with EGFR-mutated non-small cell lung cancer.”