“Dosing the first patient in the TNG348 phase 1/2 trial is an important milestone for us and for patients with advanced ovarian, breast and certain other cancers. TNG348 has the potential to become a meaningful treatment for cancers caused by DNA damage repair pathways defects,” said Barbara Weber, M.D., President and Chief Executive Officer of Tango Therapeutics. “As we begin 2024, we are hopeful for the impact we believe we can make for patients by advancing multiple synthetic lethality programs across our clinical-stage pipeline.”